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Synthesis of aza-phenylalanine, aza-tyrosine, and aza-tryptophan precursors via hydrazine alkylation; pp. 168–178
by
Mastitski, Anton
, Haljasorg, Tõiv
, Kipper, Karin
, Järv, Jaak
in
alkylation
/ aza-phenylalanine
/ aza-tryptophan
/ aza-tyrosine
/ bromination
/ hydrazine derivative
/ monoprotected hydrazine alkylation
/ precursor
/ protecting group
2015
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Synthesis of aza-phenylalanine, aza-tyrosine, and aza-tryptophan precursors via hydrazine alkylation; pp. 168–178
by
Mastitski, Anton
, Haljasorg, Tõiv
, Kipper, Karin
, Järv, Jaak
in
alkylation
/ aza-phenylalanine
/ aza-tryptophan
/ aza-tyrosine
/ bromination
/ hydrazine derivative
/ monoprotected hydrazine alkylation
/ precursor
/ protecting group
2015
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While trying to remove the title from your shelf something went wrong :( Kindly try again later!
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Synthesis of aza-phenylalanine, aza-tyrosine, and aza-tryptophan precursors via hydrazine alkylation; pp. 168–178
by
Mastitski, Anton
, Haljasorg, Tõiv
, Kipper, Karin
, Järv, Jaak
in
alkylation
/ aza-phenylalanine
/ aza-tryptophan
/ aza-tyrosine
/ bromination
/ hydrazine derivative
/ monoprotected hydrazine alkylation
/ precursor
/ protecting group
2015
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Synthesis of aza-phenylalanine, aza-tyrosine, and aza-tryptophan precursors via hydrazine alkylation; pp. 168–178
Journal Article
Synthesis of aza-phenylalanine, aza-tyrosine, and aza-tryptophan precursors via hydrazine alkylation; pp. 168–178
2015
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Overview
Aza-amino acid precursors with an aromatic side chain were synthesized using hydrazine alkylation. This synthetic pathway avoided use of hydrogen gas and expensive hydrogenation catalysts. For the optimization of this alkylation reaction various solvents and different reaction conditions were used. Aza-phenylalanine, aza-tyrosine, and aza-tryptophan precursors with different N- and side-chain protecting groups were synthesized starting from N-protected hydrazines.
Publisher
Estonian Academy Publishers
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