Journal Article

Prevalence, patterns and predictive factors of non-alcoholic fatty liver disease among morbidly obese patients undergoing sleeve gastrectomy

Bani Hani, Mohammed, Zou b, Hiba Al, Al Manasra, Abdel Rahman, Sawalmeh, Khalid Al, Khasawneh, Ruba, Alqudah, Mohammad, Qandeel, Haitham, Amir, Mohammad

2018

Overview

Discussion Over the last two decades, the increased awareness of obesity and its' related morbidities contributed to the perception of NAFLD in bariatric patients as well as in general population. Since obese patients are more likely to experience fat deposition in their livers,11 they have been investigated by multiple studies screening for NAFLD. According to the Jordan demographic health survey (2009),17 the overall prevalence of overweight was 30 per cent. In a single large, multivariable analysis of two cohorts of patients, the association between duration of adiposity and risk of type 2 DM in US women was assessed; Both overweight and obesity duration carried a significantly higher risk of Type 2 DM.23 NASH is recognized as one of the leading causes of cirrhosis in adults.24 A comparison study suggested that NASH has a fibrotic potential similar to that of chronic hepatitis C after adjustment for fibrotic confounders.25 Argo and colleagues observed bridging fibrosis in 25-33 per cent of NASH patients at diagnosis, including cirrhosis in 10-15 per cent.26 Our study showed that fibrosis was present in association with NASH in 29 per cent of cases. Since 2004, the number of adults with NASH awaiting liver transplants has almost tripled in the United States. [...]comparing our results to these studies was not amenable.

• Publisher: Australasian Medical Journal
• Subject: Age / Alcohol use / Body mass index / Diabetes / Fatty liver / Gastrointestinal surgery / Hepatitis / Hepatology / Laparoscopy / Liver cirrhosis / Liver diseases / Metabolic syndrome / Mortality / Obesity / Risk factors