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Diclofenac sodium loaded liposomal gel for transdermal delivery: Formulation, characterisation and pharmacokinetic evaluation
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Diclofenac sodium loaded liposomal gel for transdermal delivery: Formulation, characterisation and pharmacokinetic evaluation
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Journal Article
Diclofenac sodium loaded liposomal gel for transdermal delivery: Formulation, characterisation and pharmacokinetic evaluation
2018
Overview
[...]they reported that ethosomes showed higher drug concentration in the skin as compared to deformable liposomes. The average drug content value was near to 100%, indicated that there is no loss of the material during the preparation and during the storage. [...]the prepared liposomal vesicular dispersions are having enough drug content to produce the effect of the drug. [...]FTIR spectral analysis proved the compatibility of the drug and excipients used in the study. [...]it was concluded that the optimum storage condition for the liposomes was found to be between 2-8°C. Pharmacokinetic study The newly developed formulations for the existing drugs are to be evaluated for their bioavailability because in vitro testing cannot always predict the in vivo performance.
Publisher
A&V Publications
Subject
