Asset Details
Do you wish to reserve the book?
Prevalence and Antimicrobial Susceptibility Patterns of Non-fermenting Gram-Negative Bacteria Causing Lower Respiratory Tract Infections: A Retrospective Study
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Prevalence and Antimicrobial Susceptibility Patterns of Non-fermenting Gram-Negative Bacteria Causing Lower Respiratory Tract Infections: A Retrospective Study
Do you wish to request the book?
Prevalence and Antimicrobial Susceptibility Patterns of Non-fermenting Gram-Negative Bacteria Causing Lower Respiratory Tract Infections: A Retrospective Study
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Prevalence and Antimicrobial Susceptibility Patterns of Non-fermenting Gram-Negative Bacteria Causing Lower Respiratory Tract Infections: A Retrospective Study
2025
Overview
Lower respiratory tract infections (LRTIs) increase the morbidity and hospital bed occupancy. Cases of LRTI due to non-fermenting Gram-negative bacilli (NFGNB) are common in healthcare institutions. The common NFGNB found nowadays are
,
, and
. Prophylactic antibiotic use and frequent antimicrobial susceptibility testing (AST) impact the microbes' antimicrobial sensitivity patterns. We planned this study to estimate the prevalence of LRTI due to NFGNB and the antimicrobial sensitivity patterns of the causative microbes.
This retrospective study was conducted at Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, India. We analyzed data of the patients admitted between June 2023 and May 2025. We included female and male adult patients admitted to KIMS with LRTI during the study period. The specimens of bronchoalveolar lavage (BAL) fluid and endotracheal tube (ET) aspirate obtained from the qualified subjects were examined. Pathogenic bacteria were cultivated using enriched and selective media, such as 5% sheep blood agar and MacConkey agar. To identify isolates and evaluate AST, the VITEK 2 system (bioMérieux, Marcy l'Etoile, France) was employed. To analyze the data, we used R software (version 4.4.3; R Development Core Team, Vienna, Austria).
Our hospital admitted 2,389 patients with LRTI during the research period. Of them, 757 (31.69%) patients had a positive culture result for NFGNB, and 362 (47.82%) participants were female. The study population's median age was 44.79 (38.11-66.43) years. We found three non-fermenters:
(401, 52.97%),
(248, 32.76%), and
(108, 14.27%). The samples of
and
were highly sensitive to tigecycline. The cases with
were mainly sensitive to aztreonam and demonstrated the least sensitivity to colistin.
The NFGNB encountered in this study were
,
, and
.
was highly sensitive to aztreonam.
and
had maximum sensitivity for tigecycline. Future studies with bigger sample sizes must examine the pathogenic NFGNB causing LRTI and their antimicrobial susceptibility patterns.
Publisher
Springer Nature B.V,Cureus
