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Case Study of Atypical Fibroxanthoma: Presentation and Management
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Case Study of Atypical Fibroxanthoma: Presentation and Management
Case Study of Atypical Fibroxanthoma: Presentation and Management
Journal Article

Case Study of Atypical Fibroxanthoma: Presentation and Management

2024
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Overview
Atypical fibroxanthoma (AFX) is a rare spindle cell proliferation arising from significant sun exposure. AFX often appears as a red papule, typically found in the head and neck region of elderly patients. Since there is no specificity in immunohistology, various stains differentiate AFX from other skin cancers. The stains include cluster of differentiation 68 (CD68), cluster of differentiation 163 (CD163), vimentin, cytokeratin epithelial (CKAE), and melanin. While local recurrence is common, AFX rarely metastasizes. Thus, the treatment options are complete surgical excision or micrographically oriented histographic surgery.
Publisher
Springer Nature B.V