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The first example of a ring closing metathesis in a series of anthracycline antibiotics
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The first example of a ring closing metathesis in a series of anthracycline antibiotics
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The first example of a ring closing metathesis in a series of anthracycline antibiotics
The first example of a ring closing metathesis in a series of anthracycline antibiotics
Journal Article

The first example of a ring closing metathesis in a series of anthracycline antibiotics

2024
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Overview
A ring-closing metathesis giving 3-pyrroline ring in a series of anthracycline antibiotics on the example of N , N -diallyl derivative of daunorubicin using the first and the second generation Grubbs catalysts was reported. The suggested approach can be used to synthesize new anthracycline anticancer agents.