Asset Details
Do you wish to reserve the book?
Cellular uptake and cytotoxicity of unmodified Pr3+:LaF3 nanoparticles
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Cellular uptake and cytotoxicity of unmodified Pr3+:LaF3 nanoparticles
Do you wish to request the book?
Cellular uptake and cytotoxicity of unmodified Pr3+:LaF3 nanoparticles
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Cellular uptake and cytotoxicity of unmodified Pr3+:LaF3 nanoparticles
2019
Overview
Pr3+:LaF3 (CPr = 1%) nanoparticles were characterized by means of transmission electron microscopy (TEM), X-ray diffraction, energy-dispersive spectroscopy, and optical spectroscopy. The obtained 14 nm Pr3+:LaF3 (CPr = 1%) crystalline hexagonal-structured nanoparticles contain Pr, La, and F only. The luminescent spectra emission bands corresponded to the emission bands of Pr3+ions. The Pr3+:LaF3 (CPr = 1%) nanoparticles effectively interact with A 549, LEС, and MDCK cells. By means of TEM, it was revealed that after 2 h of the nanoparticle exposure, A 549, MDCK, and LEС cells internalized the nanoparticles and 20–300 nm agglomerates of the nanoparticles packed into 200–500 nm vesicles were found into the cytoplasm. It seems that the internalization occurs via macropinocytosis. In A 549 cells, some vesicles were disrupted and the nanoparticles escaped the vesicles floating freely in the cytoplasm. Flow cytometry showed that all the cells effectively interact with nanoparticles. This interaction leads to cell granularity change. Specifically, A 549, MDCK, and LEС, and cells treated by nanoparticles have the values of size scattered signal 16 ± 2, 20 ± 3, and 39 ± 3%, respectively, comparing with the untreated cells. The Pr3+:LaF3 (CPr = 1%) nanoparticles were not found into the cellular organelles. The cytotoxicity of the Pr3+:LaF3 (CPr = 1%) nanoparticles is not significant at concentrations of 0.05, 0.1, 0.25, and 0.5 g/L.
Publisher
Springer Nature B.V
Subject
We currently cannot retrieve any items related to this title. Kindly check back at a later time.