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Renal Failure in Cirrhosis
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Journal Article
Renal Failure in Cirrhosis
2009
Overview
Renal failure, a challenging complication of cirrhosis, is one of the most important risk factors for liver transplantation. In recent years, substantial progress has been made toward understanding the pathogenesis and natural history of renal failure in cirrhosis. This review discusses recently identified information about renal failure in cirrhosis and clinical interventions that may assist in the prevention and management of this complication.
Substantial progress has been made toward understanding the pathogenesis and natural history of renal failure in cirrhosis. This review discusses recently identified information about renal failure in cirrhosis and clinical interventions that may assist in the prevention and management of this complication.
Renal failure is a challenging complication of cirrhosis
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,
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and is one of the most important risk factors when liver transplantation is being considered. Patients with cirrhosis and renal failure are at high risk for death while awaiting transplantation and have an increased frequency of complications and reduced survival after transplantation, as compared with those without renal failure.
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,
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In 2002, the Model for End-Stage Liver Disease (MELD) score — derived from measurements of serum bilirubin, the international normalized ratio of prothrombin time, and serum creatinine to evaluate pretransplantation renal function — was introduced as an aid to organ allocation . . .
Publisher
Massachusetts Medical Society
Subject
Biological and medical sciences
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Humans
/ Liver Cirrhosis - complications
/ Liver. Biliary tract. Portal circulation. Exocrine pancreas
/ Nephrology. Urinary tract diseases
/ Nephropathies. Renovascular diseases. Renal failure
/ Renal Insufficiency - diagnosis
/ Renal Insufficiency - etiology
