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Bradycardia, Reversible Panconduction Defect and Syncope following Self-Medication with a Homeopathic Medicine
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Bradycardia, Reversible Panconduction Defect and Syncope following Self-Medication with a Homeopathic Medicine
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Journal Article
Bradycardia, Reversible Panconduction Defect and Syncope following Self-Medication with a Homeopathic Medicine
1999
Overview
Alkaloid extracts from the plant Aconitum species have been used in various forms of herbal remedies predominantly as anti-inflammatory and analgesic agents. Many of these alkaloids are extremely potent cardiotoxins and documented cases of various arrhythmias with fatal outcomes have been reported. We report a case of self-medication with ‘tincture of aconite’ resulting in severe bradycardia, reversible panconduction defect evidenced by sinus inactivity, atrioventricular dissociation with idiojunctional rhythm and left bundle branch block pattern resulting in hypotension and syncope. Complete reversal of ECG findings with marked improvement in symptoms was noted within a few hours. Herbal medicines containing aconite alkaloids may result in severe cardiotoxicity, and strict regulatory measures are warranted to curb unsupervised use for therapeutic purposes.
Publisher
Karger,S. Karger AG
Subject
/ Adult
/ Arrhythmia, Sinus - chemically induced
/ Arrhythmias, Cardiac - chemically induced
/ Atrioventricular Node - drug effects
/ Biological and medical sciences
/ Bradycardia - chemically induced
/ Bundle-Branch Block - chemically induced
/ Drug toxicity and drugs side effects treatment
/ Electrocardiography - drug effects
/ Humans
/ Hypotension - chemically induced
/ Male
/ Materia Medica - adverse effects
/ Pharmacology. Drug treatments
/ Plant Extracts - adverse effects
/ Self Medication - adverse effects
