Journal Article

Recombination effects in the ionization chambers dose delivery monitor of the TOP-IMPLART proton beam

Giuliani, F., Bazzano, G., Basile, E., Ronsivalle, C., Della Monaca, S., Placido, C., Spurio, A., De Angelis, C., Ampollini, A., Nenzi, P., Picardi, L., Surrenti, V., Lucentini, M., Ghio, F., Cisbani, E., Santavenere, F., Vadrucci, M.

2020

Overview

The Intensity Modulated Proton Linear Accelerator for Cancer Therapy (TOP-IMPLART) is under development and construction by ENEA in collaboration with the Italian Institute of Health (ISS) and the Oncological Hospital Regina Elena-IFO with financial support of Regione Lazio. Its peculiar time structure (few microseconds pulse width) and very high peak intensity (≍ 109 proton/pulse) demand for ad hoc dose delivery monitors (DDM). The TOP-IMPLART DDM is based on ionization gas chambers. One segmented chamber prototype uses Micro Pattern Gaseous Detector technology for the 2-dimensional simultaneous x/y readout; the charge collected from each active segment (strips with pad-like shape) is readout by a dedicated gain-adaptable electronics. Two small, highly sensitive, integral ionization chambers, using the same electronics, complement the 2D chamber for the monitor of the single pulse beam charge, down to 1 pC/pulse. While under development and deployment of its accelerating modular cavities, the linear TOP-IMPLART beam is improved thanks also to the continuous monitoring and characterization by these devices, whose responses are periodically compared to calibrated dosimetric detectors such as real-time active microDiamond sensor, passive Alanine pellets, intrinsically stable integral Faraday Cup. Different calibration campaigns have been recently conducted to measure the recombination and dose-rate effects on the above ionization chambers. The outcome of these measurements shows clear electron-ion recombination in the chamber active volume, largely related to the high beam intensity and its small transverse cross section. Those effects can be taken into account and used to correct the actual measurement of the DDM. In this paper, the TOP-IMPLART project and the DDM devices are shortly presented and details of the above experimental studies are discussed.

• Publisher: IOP Publishing
• Subject: Alanine / Dosage / Electron-ion recombination / Electronics / Gas detectors / Integrals / Ion recombination / Ionization chambers / Microdiamonds / Physics / Proton beams / Pulse duration