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m6A RNA modification as a new player in R-loop regulation
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Journal Article
m6A RNA modification as a new player in R-loop regulation
2020
Overview
RNA:DNA hybrids that form across genomes control a wide range of biological processes. A new study shows that
N
6
-methyladenosine (m
6
A) modification on the RNA moieties regulates the formation and genome integrity of these hybrids. This finding opens a new avenue of research on how RNA modifications (the ‘epitranscriptome’) can help control genome maintenance.
Publisher
Nature Publishing Group US,Nature Publishing Group
