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Journal Article
Ars Longa, Vita Brevis
2023
Overview
[...]the definitive cause of Chopin’s death has remained speculative. Given that the composer’s sister had died with a similar respiratory affliction, a genetic condition has been proposed as an alternative, the most popular being cystic fibrosis, with its autosomal recessive inheritance pattern. Not surprisingly, their assessment was that Chopin had “a serious fibrinoid epicarditis embodied by foci of epicardial hyalinization in the left ventricular front wall and with dilatation, mainly of the right ventricle and right atrium (cor pulmonale) with pronounced features of chronic heart failure, predominantly of the right ventricle,” consistent with end-stage constrictive pericarditis with fibrosis, and “several glossy, whitish-pearl nodules, slightly protruding from the surface of the myocardium,” consistent with myocardial tuberculomas. The bronzes made from the hand casts do not show clubbed fingers—thickening of the distal phalanges caused by hypoxia, characteristic of pulmonary cystic fibrosis.
Publisher
U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention
Subject
