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Metal-catalysed 1,2-diamination reactions
by
Cardona, Francesca
, Goti, Andrea
in
Aldehydes - chemistry
/ Biological Products - chemical synthesis
/ Biological Products - chemistry
/ Biological Products - pharmacology
/ Catalysis
/ Chemistry
/ Diamines - chemistry
/ Esters - chemistry
/ Hydroxylation
/ Ketones - chemistry
/ Ligands
/ Metals - chemistry
/ Natural products
/ Organic Chemicals - chemical synthesis
/ Organic Chemicals - chemistry
/ Poisoning
/ Rhodium - chemistry
2009
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Metal-catalysed 1,2-diamination reactions
by
Cardona, Francesca
, Goti, Andrea
in
Aldehydes - chemistry
/ Biological Products - chemical synthesis
/ Biological Products - chemistry
/ Biological Products - pharmacology
/ Catalysis
/ Chemistry
/ Diamines - chemistry
/ Esters - chemistry
/ Hydroxylation
/ Ketones - chemistry
/ Ligands
/ Metals - chemistry
/ Natural products
/ Organic Chemicals - chemical synthesis
/ Organic Chemicals - chemistry
/ Poisoning
/ Rhodium - chemistry
2009
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While trying to remove the title from your shelf something went wrong :( Kindly try again later!
Do you wish to request the book?
Metal-catalysed 1,2-diamination reactions
by
Cardona, Francesca
, Goti, Andrea
in
Aldehydes - chemistry
/ Biological Products - chemical synthesis
/ Biological Products - chemistry
/ Biological Products - pharmacology
/ Catalysis
/ Chemistry
/ Diamines - chemistry
/ Esters - chemistry
/ Hydroxylation
/ Ketones - chemistry
/ Ligands
/ Metals - chemistry
/ Natural products
/ Organic Chemicals - chemical synthesis
/ Organic Chemicals - chemistry
/ Poisoning
/ Rhodium - chemistry
2009
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Journal Article
Metal-catalysed 1,2-diamination reactions
2009
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Overview
The 1,2-diamine motif is present in a number of natural products with interesting biological activity and in many important pharmaceutical agents. Chiral 1,2-diamines are also widely used as the control elements in asymmetric synthesis and catalysis. Such compounds are thus an attractive target for the synthetic chemist. Although the diamination of an alkene seems an obvious route to these structures, far less research has been devoted to it than to the analogous dihydroxylation or aminohydroxylation reactions that are well-established processes in asymmetric synthesis. Here, we examine recent advances in metal-catalysed diamination reactions and their asymmetric variants. Given the prevalence of these structures, it seems likely that they will find extensive application in the construction of natural products and drug molecules in the near future.
Publisher
Nature Publishing Group
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