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Case Report: Pulmonary Alveolar Calcification as a Result of Severe Hypercalcemia due to Acute Lymphoblatic Leukemia
by
Spadaccia dos Santos Fernandes, Gustavo
, Antonio Freddi, Norberto
, Colleti Junior, Jose
, Koga, Walter
, Brunow de Carvalho, Werther
, Carla Armelin Benites, Eliana
in
Bone Biology, Osteoporosis & Other Diseases of Bone
/ Case Report
/ Leukemia & Proliferative Disorders of Hematic Cells
/ Pediatric Oncology
2015
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Case Report: Pulmonary Alveolar Calcification as a Result of Severe Hypercalcemia due to Acute Lymphoblatic Leukemia
by
Spadaccia dos Santos Fernandes, Gustavo
, Antonio Freddi, Norberto
, Colleti Junior, Jose
, Koga, Walter
, Brunow de Carvalho, Werther
, Carla Armelin Benites, Eliana
in
Bone Biology, Osteoporosis & Other Diseases of Bone
/ Case Report
/ Leukemia & Proliferative Disorders of Hematic Cells
/ Pediatric Oncology
2015
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Case Report: Pulmonary Alveolar Calcification as a Result of Severe Hypercalcemia due to Acute Lymphoblatic Leukemia
by
Spadaccia dos Santos Fernandes, Gustavo
, Antonio Freddi, Norberto
, Colleti Junior, Jose
, Koga, Walter
, Brunow de Carvalho, Werther
, Carla Armelin Benites, Eliana
in
Bone Biology, Osteoporosis & Other Diseases of Bone
/ Case Report
/ Leukemia & Proliferative Disorders of Hematic Cells
/ Pediatric Oncology
2015
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Case Report: Pulmonary Alveolar Calcification as a Result of Severe Hypercalcemia due to Acute Lymphoblatic Leukemia
Journal Article
Case Report: Pulmonary Alveolar Calcification as a Result of Severe Hypercalcemia due to Acute Lymphoblatic Leukemia
2015
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Overview
Severe hypercalcemia is a rare metabolic disorder in pediatric medicine. This report describes a rare case of severe hypercalcemia and its clinical manifestations in a 2-year-old toddler. The radiological findings caused by hypercalcemia and osteolysis were emblematic of the osteolytic lesions. Hypercalcemia led to massive pulmonary alveolar calcification. The hypercalcemia was successfully treated with pamidronate, a bisphosphonate drug class. Further investigation resulted in a diagnosis of acute lymphoblastic leukemia (ALL). The patient is currently on chemotherapy and has a favorable prognosis. Although severe hypercalcemia alone is an unusual finding as the first sign for ALL, this should be considered, not to mention the radiological images resulted from calcium deposits.
Publisher
F1000Research,F1000 Research Ltd
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