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Pharmacogenetics of methotrexate response in rheumatoid arthritis: an update
by
Ling, Stephanie F
, Bluett, James
in
Antirheumatic Agents - adverse effects
/ Antirheumatic Agents - therapeutic use
/ Arthritis, Rheumatoid - drug therapy
/ Arthritis, Rheumatoid - genetics
/ Biomarkers
/ Biomarkers - metabolism
/ C-reactive protein
/ Disease
/ DMARD
/ Erythrocyte sedimentation rate
/ Gene expression
/ genetics
/ Genomes
/ Humans
/ Immunomodulators
/ Inflammation
/ Joint diseases
/ Metabolism
/ Methotrexate
/ Methotrexate - adverse effects
/ Methotrexate - therapeutic use
/ Patients
/ Pharmacogenetics
/ Polymorphism
/ Precision Medicine
/ Rheumatoid arthritis
/ Studies
/ treatment response
2020
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Pharmacogenetics of methotrexate response in rheumatoid arthritis: an update
by
Ling, Stephanie F
, Bluett, James
in
Antirheumatic Agents - adverse effects
/ Antirheumatic Agents - therapeutic use
/ Arthritis, Rheumatoid - drug therapy
/ Arthritis, Rheumatoid - genetics
/ Biomarkers
/ Biomarkers - metabolism
/ C-reactive protein
/ Disease
/ DMARD
/ Erythrocyte sedimentation rate
/ Gene expression
/ genetics
/ Genomes
/ Humans
/ Immunomodulators
/ Inflammation
/ Joint diseases
/ Metabolism
/ Methotrexate
/ Methotrexate - adverse effects
/ Methotrexate - therapeutic use
/ Patients
/ Pharmacogenetics
/ Polymorphism
/ Precision Medicine
/ Rheumatoid arthritis
/ Studies
/ treatment response
2020
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Do you wish to request the book?
Pharmacogenetics of methotrexate response in rheumatoid arthritis: an update
by
Ling, Stephanie F
, Bluett, James
in
Antirheumatic Agents - adverse effects
/ Antirheumatic Agents - therapeutic use
/ Arthritis, Rheumatoid - drug therapy
/ Arthritis, Rheumatoid - genetics
/ Biomarkers
/ Biomarkers - metabolism
/ C-reactive protein
/ Disease
/ DMARD
/ Erythrocyte sedimentation rate
/ Gene expression
/ genetics
/ Genomes
/ Humans
/ Immunomodulators
/ Inflammation
/ Joint diseases
/ Metabolism
/ Methotrexate
/ Methotrexate - adverse effects
/ Methotrexate - therapeutic use
/ Patients
/ Pharmacogenetics
/ Polymorphism
/ Precision Medicine
/ Rheumatoid arthritis
/ Studies
/ treatment response
2020
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Pharmacogenetics of methotrexate response in rheumatoid arthritis: an update
Journal Article
Pharmacogenetics of methotrexate response in rheumatoid arthritis: an update
2020
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Overview
[...]it is vital that baseline characteristics predictive of response to MTX are discovered to prevent long-term disability. The DAS28 is a weighted score of the number of tender and swollen joints out of 28, the patient’s global assessment of arthritis activity on a visual analog scale (VAS, 0-100mm) and a biochemical maker of inflammation (erythrocyte sedimentation rate, ESR or C-reactive protein, CRP). [...]predicting MTX response and developing stratified medicine techniques is vital. [...]there is variation in treatment outcome measures between studies and most utilize the DAS28, which includes subjective patient-reported outcome measures (TJC, VAS), as previously discussed.
Publisher
Future Medicine Ltd
Subject
Antirheumatic Agents - adverse effects
/ Antirheumatic Agents - therapeutic use
/ Arthritis, Rheumatoid - drug therapy
/ Arthritis, Rheumatoid - genetics
/ Disease
/ DMARD
/ Erythrocyte sedimentation rate
/ genetics
/ Genomes
/ Humans
/ Methotrexate - adverse effects
/ Methotrexate - therapeutic use
/ Patients
/ Studies
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