Asset Details
Do you wish to reserve the book?
Analysis, expression and prevalence of the Mycobacterium tuberculosis homolog of bacterial virulence regulating proteins
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Analysis, expression and prevalence of the Mycobacterium tuberculosis homolog of bacterial virulence regulating proteins
Do you wish to request the book?
Analysis, expression and prevalence of the Mycobacterium tuberculosis homolog of bacterial virulence regulating proteins
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Analysis, expression and prevalence of the Mycobacterium tuberculosis homolog of bacterial virulence regulating proteins
1999
Overview
Abstract
We have previously reported the identification of a gene from Mycobacterium tuberculosis, H37Rv, which on the basis of its nucleotide sequence encoded a protein product of 38 kDa. This 38-Kda mycobacterial protein designated as VirS exhibits homology with the VirF protein of Shigella, the VirFy protein of Yersinia and the Cfad, Rns and FapR proteins from various enterotoxigenic Escherichia coli strains. In this communication, we show the close sequence and structural similarities of the VirS protein with VirF, VirFy, Cfad, Rns and FapR and describe the results of our studies on the characterization of the virS gene promoter and its expression in E. coli and mycobacteria. virS was present exclusively in the species belonging to the M. tuberculosis complex as revealed by Southern blot and PCR analysis. Our findings suggest the involvement of virS in the regulation of pathogenesis of M. tuberculosis.
Publisher
Blackwell Publishing Ltd,Blackwell,Oxford University Press
Subject
/ Bacterial Proteins - genetics
/ Biological and medical sciences
/ E coli
/ Electrophoresis, Polyacrylamide Gel
/ Fundamental and applied biological sciences. Psychology
/ Gene Expression Regulation, Bacterial
/ Genetics
/ Homology
/ Mycobacterium tuberculosis - genetics
/ Mycobacterium tuberculosis - pathogenicity
/ Promoter Regions, Genetic - genetics
/ Proteins
