Asset Details
Do you wish to reserve the book?
Susceptibility of Anaerobic Bacteria to Carbenicillin, Cefoxitin, and Related Drugs
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Susceptibility of Anaerobic Bacteria to Carbenicillin, Cefoxitin, and Related Drugs
Do you wish to request the book?
Susceptibility of Anaerobic Bacteria to Carbenicillin, Cefoxitin, and Related Drugs
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Susceptibility of Anaerobic Bacteria to Carbenicillin, Cefoxitin, and Related Drugs
1975
Overview
The agar dilution technique was used for determination of the bacteriostatic activity of carbenicillin, penicillin G, cefazolin, cephaloridine, cefoxitin, and cephalothin against a variety of anaerobic bacteria. Carbenicillin showed a high level of activity at a concentration of ⩽ 100 µg/ml; only five of 123 strains of Bacteroides fragilis, one strain of Bifidobacterium eriksonii, and one strain of Clostridium bifermentans were resistant to a concentration of ⩾ 100 µg/ml. Cefoxitin, a β-lactamase-resistant drug, was highly active against B. fragilis and most other anaerobes at a concentration of ⩽ 32 µg/ml; the exceptions were one strain of Bacteroides species and 13 of 28 strains of Clostridium species. The other cephalosporins were less active against B. fragilis but exhibited good activity against most of the other strains tested. Bactericidal concentrations of cefoxitin and cephalothin were determined for 51 selected strains by the broth dilution technique, and the activities of these drugs were compared with those of two other drugs (clindamycin and metronidazole) known to be very active against anaerobes. Metronidazole was the most consistently bactericidal of the four drugs tested for this activity.
Publisher
The University of Chicago Press,University of Chicago Press
