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Common Medications Which Lead to Unintended Alterations in Weight Gain or Organ Lipotoxicity
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Journal Article
Common Medications Which Lead to Unintended Alterations in Weight Gain or Organ Lipotoxicity
2016
Overview
Obesity is one of the most common chronic conditions in the world. Its management is difficult, partly due to the multiple associated comorbidities including fatty liver, diabetes, hypertension, and hyperlipidemia. As a result, the choice of prescription medications in overweight and obese patients has important implications as some of them can actually worsen the fat accumulation and its associated metabolic complications. Several prescription medications are associated with weight gain with mechanisms that are often poorly understood and under-recognized. Even less data are available on the distribution of fat and lipotoxicity (the organ damage related to fat accumulation). The present review will discuss the drugs associated with weight gain, their mechanism of action, and the magnitude and timing of their effect.
Publisher
Springer US,Springer Nature B.V
Subject
/ Anti-Inflammatory Agents - adverse effects
/ Antidepressive Agents - adverse effects
/ Antihypertensive Agents - adverse effects
/ Antipsychotic Agents - adverse effects
/ Body fat
/ Contraceptives, Oral - adverse effects
/ Diabetes
/ Glucose
/ Humans
/ Hypoglycemic Agents - adverse effects
/ Lipid Metabolism - drug effects
/ Lipids
/ Liver
/ Medicine
/ Nutrition and Obesity (SA McClave
/ Obesity
/ Obesity - chemically induced
/ Topical Collection on Nutrition and Obesity
/ Trends
