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Covid-19 Boosters — Where from Here?
by
Offit, Paul A
in
Age groups
/ Asymptomatic
/ Coronavirus
/ Coronaviruses
/ COVID-19
/ COVID-19 - prevention & control
/ COVID-19 vaccines
/ Disease control
/ Disease transmission
/ Epidemiology
/ Humans
/ Illnesses
/ Immunization, Secondary
/ Immunological memory
/ Infectious Disease
/ Lymphocytes T
/ Medical research
/ Memory cells
/ mRNA
/ mRNA vaccines
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Vaccines
/ Viral Infections
2022
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Covid-19 Boosters — Where from Here?
by
Offit, Paul A
in
Age groups
/ Asymptomatic
/ Coronavirus
/ Coronaviruses
/ COVID-19
/ COVID-19 - prevention & control
/ COVID-19 vaccines
/ Disease control
/ Disease transmission
/ Epidemiology
/ Humans
/ Illnesses
/ Immunization, Secondary
/ Immunological memory
/ Infectious Disease
/ Lymphocytes T
/ Medical research
/ Memory cells
/ mRNA
/ mRNA vaccines
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Vaccines
/ Viral Infections
2022
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Do you wish to request the book?
Covid-19 Boosters — Where from Here?
by
Offit, Paul A
in
Age groups
/ Asymptomatic
/ Coronavirus
/ Coronaviruses
/ COVID-19
/ COVID-19 - prevention & control
/ COVID-19 vaccines
/ Disease control
/ Disease transmission
/ Epidemiology
/ Humans
/ Illnesses
/ Immunization, Secondary
/ Immunological memory
/ Infectious Disease
/ Lymphocytes T
/ Medical research
/ Memory cells
/ mRNA
/ mRNA vaccines
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Vaccines
/ Viral Infections
2022
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Journal Article
Covid-19 Boosters — Where from Here?
2022
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Overview
On December 10, 2020, Pfizer presented results from a 36,000-person, two-dose, prospective, placebo-controlled trial of its Covid-19 messenger RNA (mRNA) vaccine, BNT162b2, to the Food and Drug Administration (FDA).
1
The vaccine was 95% effective at preventing severe illness in all age groups, independent of coexisting conditions or racial or ethnic background. A remarkable result. Six months later, studies showed that protection against severe disease was holding up.
2
The results of these epidemiologic studies were consistent with those of immunologic studies showing long-lived, high frequencies of Covid-19–specific memory B and T cells, which mediate protection against severe disease.
3
In September 2021, . . .
Publisher
Massachusetts Medical Society
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