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Covid-19 Boosters — Where from Here?
Covid-19 Boosters — Where from Here?
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Covid-19 Boosters — Where from Here?
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Covid-19 Boosters — Where from Here?
Covid-19 Boosters — Where from Here?

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Covid-19 Boosters — Where from Here?
Covid-19 Boosters — Where from Here?
Journal Article

Covid-19 Boosters — Where from Here?

2022
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Overview
On December 10, 2020, Pfizer presented results from a 36,000-person, two-dose, prospective, placebo-controlled trial of its Covid-19 messenger RNA (mRNA) vaccine, BNT162b2, to the Food and Drug Administration (FDA). 1 The vaccine was 95% effective at preventing severe illness in all age groups, independent of coexisting conditions or racial or ethnic background. A remarkable result. Six months later, studies showed that protection against severe disease was holding up. 2 The results of these epidemiologic studies were consistent with those of immunologic studies showing long-lived, high frequencies of Covid-19–specific memory B and T cells, which mediate protection against severe disease. 3 In September 2021, . . .