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Journal Article
Should reperfusion be revisited?
2016
Overview
The landmark studies of Kloner [5,6], Yellon, and others [7,8] clarified the hypothesis that this injury was fueled by the restoration of blood flow during resuscitation of patients in the setting of acute myocardial infarction, stroke, and cardiac arrest. The possibility that the combination of therapeutic hypothermia and the mechanistically-attractive-but-clinical-trial-failing pharma agents may be effective for ischemia-reperfusion injury may be the most exciting thing to happen in the field in quite some time.
Publisher
Elsevier Inc,Elsevier Limited
