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Outcome and survival were similar with laparoscopic and open pancreatectomy in 102 solid pseudopapillary neoplasms
by
Rebours, Vinciane
, Marique, Lancelot
, de Mestier, Louis
, Codjia, Tatiana
, Dokmak, Safi
, Ruszniewski, Philippe
, Lévy, Philippe
, Lesurtel, Mickael
, Cros, Jérome
, Aussilhou, Béatrice
, Ftériche, Fadhel Samir
, Sauvanet, Alain
in
Laparoscopy
/ Lymphatic system
/ Pancreas
/ Pancreatectomy
/ Surgical outcomes
/ Tumors
2024
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Outcome and survival were similar with laparoscopic and open pancreatectomy in 102 solid pseudopapillary neoplasms
by
Rebours, Vinciane
, Marique, Lancelot
, de Mestier, Louis
, Codjia, Tatiana
, Dokmak, Safi
, Ruszniewski, Philippe
, Lévy, Philippe
, Lesurtel, Mickael
, Cros, Jérome
, Aussilhou, Béatrice
, Ftériche, Fadhel Samir
, Sauvanet, Alain
in
Laparoscopy
/ Lymphatic system
/ Pancreas
/ Pancreatectomy
/ Surgical outcomes
/ Tumors
2024
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Outcome and survival were similar with laparoscopic and open pancreatectomy in 102 solid pseudopapillary neoplasms
by
Rebours, Vinciane
, Marique, Lancelot
, de Mestier, Louis
, Codjia, Tatiana
, Dokmak, Safi
, Ruszniewski, Philippe
, Lévy, Philippe
, Lesurtel, Mickael
, Cros, Jérome
, Aussilhou, Béatrice
, Ftériche, Fadhel Samir
, Sauvanet, Alain
in
Laparoscopy
/ Lymphatic system
/ Pancreas
/ Pancreatectomy
/ Surgical outcomes
/ Tumors
2024
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Outcome and survival were similar with laparoscopic and open pancreatectomy in 102 solid pseudopapillary neoplasms
Journal Article
Outcome and survival were similar with laparoscopic and open pancreatectomy in 102 solid pseudopapillary neoplasms
2024
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Overview
BackgroundSolid pseudopapillary neoplasms of the pancreas (SPNP) are rare tumors predominantly in young women. We report the largest single-center cohort study comparing resection of SPNP by laparoscopic approach (LA) and the open approach (OA).MethodBetween 2001 and 2021, 102 patients (84% women, median age: 30) underwent pancreatectomy for SPNP and were retrospectively studied. Demographic, perioperative, pathological, early and the long-term results were evaluated between patients operated by LA and those by OA.ResultsPopulation included 40 LA and 62 OA. There were no significant differences in demographics data between the groups. A preoperative biopsy by endoscopic ultrasound was performed in 45 patients (44%) with no difference between the groups. Pancreatoduodenectomy (PD) was less frequently performed by LA (25 vs 53%, p = 0.004) and distal pancreatectomy (DP) was more frequently performed by LA (40 vs 16%, p = 0.003). In the subgroup analysis by surgical procedure, LA-PD was associated with one mortality, less median blood loss (180 vs 200 ml, p = 0.034) and fewer harvested lymph nodes (11 vs 15, p = 0.02). LA-DP was associated with smaller median tumor size on imaging (40 vs 80mm, p = 0.048), shorter surgery (135 vs 190 min, p = 0.028), and fewer complications according to the median comprehensive complication index score (0 vs 8.7, p = 0.048). LA-Central pancreatectomy was associated with shorter surgery (160 vs 240, p = 0.037), less median blood loss (60 vs 200, p = 0.043), and less harvested lymph nodes (5 vs 2, p = 0.025). After a median follow-up of 60 months, two recurrences (2%) were observed and were unrelated to the approach.ConclusionsThe LA for SPNP appears to be safe, should be applied cautiously in case of PD for large lesion, and was not associated with recurrence.
Publisher
Springer Nature B.V
Subject
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