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Domino ring opening and selective O/S-alkylation of cyclic ethers and thioethers
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Domino ring opening and selective O/S-alkylation of cyclic ethers and thioethers
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Journal Article
Domino ring opening and selective O/S-alkylation of cyclic ethers and thioethers
2021
Overview
Chemoselective domino ring opening and selective O/S-alkylation of ethers/thioethers over enol C/O alkylation has been observed. Various 2-aryl chromanones/thiochromanones with alkyl/allyl bromides were smoothly converted into the corresponding highly functionalized ethers and thioethers in excellent yields with high selectivity.Graphic abstractAn unusual, chemoselective domino ring opening and selective ether/thioether O/S-alkylation over. An unusual, chemoselective domino ring opening and selective ether/thioether O/S alkylation over enol C/O alkylation has been observed.
Publisher
Springer Nature B.V
Subject
