Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Impact of Nutritional Status on Severe Radiation-Induced Mucositis in Oropharyngeal Cancer Patients Undergoing Chemo-Radiotherapy

by Toledo-Serrano, María Dolores , De la Peña-Fernández, Lourdes , Jiménez-Rodríguez, Herminda , García-Almeida, José Manuel , Muñoz-Lupiáñez, Marina , Ruiz-López, María Asunción , Fernández-Forné, África , Fernández-Jiménez, Rocío , Queipo-Ortuño, María Isabel , Gómez-Millán, Jaime

in Aged / Analysis / Body composition / Cancer / Cancer patients / Cancer therapies / Care and treatment / Chemoradiotherapy - adverse effects / Chemotherapy / Cohort analysis / Development and progression / Female / Head & neck cancer / Humans / Male / Malnutrition / Medical prognosis / Middle Aged / Mucositis / Mucositis - etiology / Nutrition / Nutrition Assessment / Nutritional Status / Oncology / Oropharyngeal Neoplasms - radiotherapy / Oropharyngeal Neoplasms - therapy / Ostomy / Patients / Product/Service Evaluations / Prospective Studies / Quality of life / Radiation / Radiation Injuries - etiology / Radiation therapy / Radiotherapy / Risk Factors / Squamous cell carcinoma / Variables

2025

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Impact of Nutritional Status on Severe Radiation-Induced Mucositis in Oropharyngeal Cancer Patients Undergoing Chemo-Radiotherapy

2025

Confirm

Do you wish to request the book?

Impact of Nutritional Status on Severe Radiation-Induced Mucositis in Oropharyngeal Cancer Patients Undergoing Chemo-Radiotherapy

2025

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Impact of Nutritional Status on Severe Radiation-Induced Mucositis in Oropharyngeal Cancer Patients Undergoing Chemo-Radiotherapy

Toledo-Serrano, María Dolores,

De la Peña-Fernández, Lourdes,

Jiménez-Rodríguez, Herminda,

García-Almeida, José Manuel,

Muñoz-Lupiáñez, Marina,

Ruiz-López, María Asunción,

Fernández-Forné, África,

Fernández-Jiménez, Rocío,

Queipo-Ortuño, María Isabel,

Gómez-Millán, Jaime

2025

Overview

Background/Objectives: Severe radiation-induced mucositis (RIM) is the most distressing acute side effect experienced by oropharyngeal squamous cell carcinoma (OPSCC) patients during chemo-radiotherapy (CRT), with a prevalence between 40 and 68%. RIM severity exhibits a multifactorial etiology that remains unclear. We aimed to analyze nutritional and morphofunctional predictive factors for severe RIM in OPSCC patients undergoing CRT. Methods: A prospective cohort study was conducted. Global Leadership Initiative on Malnutrition (GLIM) criteria, bioelectrical impedance vector analysis (BIVA), functional assessment and dosimetric analysis were performed prior to radiotherapy. Results: Eighty-two patients were analyzed. Severe RIM affected 46.3% of patients. Severe malnutrition according to GLIM (p = 0.011), prolonged Timed Up and Go (TUG) test (p = 0.025) and larger PTV54 volume (p = 0.049) were independent predictive factors for severe RIM, while higher fat-free mass (FFM) (p = 0.006) showed a protective effect. Conclusions: These findings highlight the importance of a comprehensive early nutritional assessment for accurately identifying patients at a higher risk of severe RIM.

Share this book

Add to My Shelf

Publisher

MDPI AG

Subject

/ Cancer