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Characterizing Trends of Lymphedema After Axillary Lymph Node Dissection with and Without Immediate Lymphatic Reconstruction
by
Chu, Michael W.
, Chang, Jeff
, Sam, Andre-Philippe
, Vangsness, Kella L.
, Mehta, Yash A.
, Agko, Mouchammed
, Carré, Antoine L.
in
Body mass index
/ Breast cancer
/ California
/ Cancer therapies
/ Care and treatment
/ Chi-square test
/ Comorbidity
/ Dissection
/ Ethnicity
/ Health aspects
/ Lymph nodes
/ Lymphatic system
/ Lymphedema
/ Morbidity
/ Mortality
/ Patients
/ Radiation
/ Regression analysis
/ Surgery
/ Variables
/ Veins & arteries
2025
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Characterizing Trends of Lymphedema After Axillary Lymph Node Dissection with and Without Immediate Lymphatic Reconstruction
by
Chu, Michael W.
, Chang, Jeff
, Sam, Andre-Philippe
, Vangsness, Kella L.
, Mehta, Yash A.
, Agko, Mouchammed
, Carré, Antoine L.
in
Body mass index
/ Breast cancer
/ California
/ Cancer therapies
/ Care and treatment
/ Chi-square test
/ Comorbidity
/ Dissection
/ Ethnicity
/ Health aspects
/ Lymph nodes
/ Lymphatic system
/ Lymphedema
/ Morbidity
/ Mortality
/ Patients
/ Radiation
/ Regression analysis
/ Surgery
/ Variables
/ Veins & arteries
2025
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Do you wish to request the book?
Characterizing Trends of Lymphedema After Axillary Lymph Node Dissection with and Without Immediate Lymphatic Reconstruction
by
Chu, Michael W.
, Chang, Jeff
, Sam, Andre-Philippe
, Vangsness, Kella L.
, Mehta, Yash A.
, Agko, Mouchammed
, Carré, Antoine L.
in
Body mass index
/ Breast cancer
/ California
/ Cancer therapies
/ Care and treatment
/ Chi-square test
/ Comorbidity
/ Dissection
/ Ethnicity
/ Health aspects
/ Lymph nodes
/ Lymphatic system
/ Lymphedema
/ Morbidity
/ Mortality
/ Patients
/ Radiation
/ Regression analysis
/ Surgery
/ Variables
/ Veins & arteries
2025
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Characterizing Trends of Lymphedema After Axillary Lymph Node Dissection with and Without Immediate Lymphatic Reconstruction
Journal Article
Characterizing Trends of Lymphedema After Axillary Lymph Node Dissection with and Without Immediate Lymphatic Reconstruction
2025
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Overview
Background and Objectives: Breast cancer-related lymphedema (BCRL) is a complication of axillary lymph node dissection (ALND). Immediate lymphatic reconstruction (ILR) may help to decrease lymphedema after ALND by creating lymphatic bypasses. This retrospective single-institution study aimed to compare lymphedema in patients undergoing ALND with and without ILR. Materials and Methods: Bioimpedance and limb measurements determined the presence of BCRL. The categorical data that were collected and analyzed included BMI, comorbidities, BCRL onset, and number of lymphatic bypasses. Pearson’s chi-square test and multivariable logistic regression were performed to identify factors associated with the onset of lymphedema. An odds ratio compared the incidence of BCRL with and without ILR. Results: In total, 186 patients underwent ALND, 44 (24%) with ILR and 142 (76%) without. The mean number of bypasses during ILRs created was 3.54. The odds of developing lymphedema with ILR were 64% lower than for ALND alone. ILR patients who developed BCRL had a mean onset of 543 days post-operatively versus 389 days in the control group. Age, ethnicity, BMI, and bypass amount had no significant influence on lymphedema development. Conclusions: ILR was associated with lower rates of BCRL after ALND. Patients who developed lymphedema despite undergoing ILR did so 8 months later than the controls.
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