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Statistical Power and the Classical Twin Design
by
Neale, Benjamin M.
, Sham, Pak C.
, Cherny, Stacey S.
, Neale, Michael C.
, Purcell, Shaun M.
in
Expected values
/ Genetics, Behavioral - history
/ Genetics, Behavioral - statistics & numerical data
/ History, 20th Century
/ History, 21st Century
/ Humans
/ Martin Nick
/ Quantitative genetics
/ Sample Size
/ Statistical analysis
/ Statistical power
/ Statistical significance
/ Statistics
/ Twin studies
/ Twin Studies as Topic - history
/ Twin Studies as Topic - statistics & numerical data
/ Twins
/ Twins - genetics
/ Twins - statistics & numerical data
2020
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Statistical Power and the Classical Twin Design
by
Neale, Benjamin M.
, Sham, Pak C.
, Cherny, Stacey S.
, Neale, Michael C.
, Purcell, Shaun M.
in
Expected values
/ Genetics, Behavioral - history
/ Genetics, Behavioral - statistics & numerical data
/ History, 20th Century
/ History, 21st Century
/ Humans
/ Martin Nick
/ Quantitative genetics
/ Sample Size
/ Statistical analysis
/ Statistical power
/ Statistical significance
/ Statistics
/ Twin studies
/ Twin Studies as Topic - history
/ Twin Studies as Topic - statistics & numerical data
/ Twins
/ Twins - genetics
/ Twins - statistics & numerical data
2020
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Do you wish to request the book?
Statistical Power and the Classical Twin Design
by
Neale, Benjamin M.
, Sham, Pak C.
, Cherny, Stacey S.
, Neale, Michael C.
, Purcell, Shaun M.
in
Expected values
/ Genetics, Behavioral - history
/ Genetics, Behavioral - statistics & numerical data
/ History, 20th Century
/ History, 21st Century
/ Humans
/ Martin Nick
/ Quantitative genetics
/ Sample Size
/ Statistical analysis
/ Statistical power
/ Statistical significance
/ Statistics
/ Twin studies
/ Twin Studies as Topic - history
/ Twin Studies as Topic - statistics & numerical data
/ Twins
/ Twins - genetics
/ Twins - statistics & numerical data
2020
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Journal Article
Statistical Power and the Classical Twin Design
2020
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Overview
Dr Nick Martin has made enormous contributions to the field of behavior genetics over the past 50 years. Of his many seminal papers that have had a profound impact, we focus on his early work on the power of twin studies. He was among the first to recognize the importance of sample size calculation before conducting a study to ensure sufficient power to detect the effects of interest. The elegant approach he developed, based on the noncentral chi-squared distribution, has been adopted by subsequent researchers for other genetic study designs, and today remains a standard tool for power calculations in structural equation modeling and other areas of statistical analysis. The present brief article discusses the main aspects of his seminal paper, and how it led to subsequent developments, by him and others, as the field of behavior genetics evolved into the present era.
Publisher
Cambridge University Press
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