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Journal Article
Is the next generation of mosquito nets surviving expectations?
2024
Overview
[...]to the trial in Tanzania,5 the authors now report in The Lancet Infectious Diseases that in Benin,6 the added benefit of the chlorfenapyr ITNs did not extend to the third year after distribution even though a considerably higher percentage of study nets remained in use at 36 months (52% in Benin vs 31% in Tanzania). Countries without substantial agricultural insecticide usage, such as Papua New Guinea, have not seen resistance emerge even after two decades of intensive ITN mass distributions on the same scale as in sub-Saharan Africa.9 As such, it seems worthwhile to explore opportunities to reserve specific insecticide classes for disease vector control; however, there is little economic incentive to develop new chemistries exclusively for public health. ITN coverage has remained largely unchanged since 2015, a trend that coincided with the stagnation of global malaria reduction.12 The work by Accrombessi and colleagues demonstrates that current chlorfenpyr ITNs have a stronger impact on malaria transmission in areas with pyrethroid resistance, but the added benefit is lost after 2 years, when the coverage, and therefore usage, of these nets becomes too low to exert population level effects on mosquitoes.
Publisher
Elsevier Ltd,Elsevier Limited
Subject
