Journal Article

Prevalence of Coxiella burnetii (Q fever) antibodies in bovine serum and bulk-milk samples

SAYERS, R., KIRBY, M., COLLINS, D. M., MEE, J. F., RYAN, E. D., CLEGG, T.

2011

Overview

Q fever ( Coxiella burnetii ) is a zoonotic disease of increasing public health importance. The objective of this study was to estimate the prevalence of, and risk factors associated with, exposure to C. burnetii in cattle in the Republic of Ireland. Bulk-tank milk samples from 290 dairy herds and 1659 sera from 332 dairy and beef herds, randomly sampled, were tested by indirect ELISA to detect antibodies to C. burnetii . In total, 37·9% of bulk-milk sample herds and 1·8% of sera (from 6·9% of herds) were antibody positive. Of risk factors tested using logistic regression analysis, only large herd size (bulk-milk analysis) and dairy breed (serum analysis) significantly increased the odds of being positive for antibodies to C. burnetii . Herds with positive milk or serum samples were randomly distributed throughout the Republic of Ireland and no clustering was observed. The use of an ELISA to test bulk-milk samples collected by randomized stratified sampling is a cost-effective method by which national herd prevalence can be estimated by active surveillance.

• Publisher: Cambridge University Press
• Subject: Animals / Antibodies / Antibodies, Bacterial - blood / Antibodies, Bacterial - immunology / Bacterial diseases / Bacteriology / Beef / Biological and medical sciences / Cattle / Coxiella burnetii - immunology / Farms / Fever / Fundamental and applied biological sciences. Psychology / Human bacterial diseases / Infectious diseases / Medical sciences / Microbiology / Milk / Milk - microbiology / Miscellaneous / Prevalence / Public health / Q Fever - epidemiology / Q Fever - immunology / Regression analysis / Rickettsial diseases / Risk Factors / Serology / Sheep / Surveillance / Tropical bacterial diseases / Variables