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Enteroviral Meningoencephalitis after Anti-CD20 (Rituximab) Treatment

by Tardieu, Marc , Quartier, Pierre , Travade, Philippe , Chaleteix, Carine , Archimbaud, Christine , Fischer, Alain , Lazaro, Leila , Peigue-Lafeuille, Hélène , Casanova, Jean-Laurent , Tournilhac, Olivier , Blanche, Stéphane , Millet, Pascale

in Antibodies, Monoclonal - adverse effects / Antibodies, Monoclonal, Murine-Derived / Antigens, CD20 - immunology / Antineoplastic Agents - adverse effects / Child / Humans / Meningoencephalitis - chemically induced / Middle Aged / Rituximab

2003

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Enteroviral Meningoencephalitis after Anti-CD20 (Rituximab) Treatment

2003

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Enteroviral Meningoencephalitis after Anti-CD20 (Rituximab) Treatment

2003

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Journal Article

Enteroviral Meningoencephalitis after Anti-CD20 (Rituximab) Treatment

Tardieu, Marc,

Quartier, Pierre,

Travade, Philippe,

Chaleteix, Carine,

Archimbaud, Christine,

Fischer, Alain,

Lazaro, Leila,

Peigue-Lafeuille, Hélène,

Casanova, Jean-Laurent,

Tournilhac, Olivier,

Blanche, Stéphane,

Millet, Pascale

2003

Overview

Treatment with the chimeric anti-CD20 monoclonal antibody rituximab induces rapid and long-lasting depletion of circulating B cells. We report the occurrence of enteroviral meningoencephalitis following rituximab therapy in 1 child with immune thrombocytopenia and in 1 adult patient with relapsed B cell lymphoma.

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Publisher

The University of Chicago Press

Subject

Antibodies, Monoclonal - adverse effects

/ Antibodies, Monoclonal, Murine-Derived

/ Antigens, CD20 - immunology

/ Antineoplastic Agents - adverse effects

/ Child

/ Humans

/ Meningoencephalitis - chemically induced