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Lifelong medical challenges and immunogenetics of Turner syndrome
by
Cho, Won Kyoung
in
immunogenetics
/ Review
/ turner syndrome
/ x chromosome
/ 소아과학
2024
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Lifelong medical challenges and immunogenetics of Turner syndrome
by
Cho, Won Kyoung
in
immunogenetics
/ Review
/ turner syndrome
/ x chromosome
/ 소아과학
2024
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Lifelong medical challenges and immunogenetics of Turner syndrome
Journal Article
Lifelong medical challenges and immunogenetics of Turner syndrome
2024
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Overview
Turner syndrome (TS) is a female phenotypic condition characterized by one or more typical clinical features and the partial or complete absence of a second X chromosome as determined by karyotype analysis. TS, among the most common chromosomal abnormalities, has an estimated prevalence of approximately 1 in 2,500 live-born females, with ethnic and racial differences. TS encompasses a wide array of medical challenges, including cardiovascular, endocrine, autoimmune, and mental health issues, as well as a heightened cancer risk. The somatic stigmata of TS are thought to arise from haploinsufficiency of the X chromosomes. This review explores the lifelong medical challenges and immunogenetics of individuals with TS and aimed to investigate strategies for preventing and managing TS while considering the implications of immunogenetics.
Publisher
Korean Pediatric Society,The Korean Pediatric Society,대한소아청소년과학회
Subject
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