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Safety and efficacy of transurethral holmium laser enucleation of the prostate versus bipolar transurethral resection of the prostate in the treatment of benign prostatic hyperplasia: a prospective randomized controlled trial
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Safety and efficacy of transurethral holmium laser enucleation of the prostate versus bipolar transurethral resection of the prostate in the treatment of benign prostatic hyperplasia: a prospective randomized controlled trial
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Safety and efficacy of transurethral holmium laser enucleation of the prostate versus bipolar transurethral resection of the prostate in the treatment of benign prostatic hyperplasia: a prospective randomized controlled trial
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Journal Article
Safety and efficacy of transurethral holmium laser enucleation of the prostate versus bipolar transurethral resection of the prostate in the treatment of benign prostatic hyperplasia: a prospective randomized controlled trial
2024
Overview
Purpose
To evaluate the safety and efficacy of transurethral holmium laser enucleation of the prostate (HoLEP) compared to bipolar transurethral resection of the prostate (bTUR-P) in the treatment of benign prostatic hyperplasia (BPH).
Methods
A total of 220 BPH patients hospitalized from January 2022 to September 2023 were included in this study. These patients were randomly assigned to HoLEP and bTUR-P groups, with 110 participants in each group. We collected preoperative general information, perioperative data, complications, and postoperative follow-up indicators from both groups of patients.
Results
The baseline characteristics of patients in both groups were similar, with no statistical significance (
P
> 0.05). Compared to the bTUR-P group, the HoLEP group exhibited significantly less intraoperative bleeding (
P
< 0.001), shorter bladder irrigation time (
P
= 0.002), shorter catheter retention time (
P
< 0.001), and reduced postoperative hospitalization (
P
= 0.002). Additionally, the pain score during urination after catheter removal was significantly lower in the HoLEP group (
P
< 0.001). Postoperative complications occurred in both groups; however, they were less frequent in the HoLEP group (4 cases), primarily consisting of urinary retention and postoperative bleeding. The bTUR-P group experienced more complications (9 cases). Significant reductions in postoperative residual urine volume (RUV) were observed in both groups (
P
< 0.001). Both groups also showed significant improvements in Quality of Life (QoL) scores and International Prostate Symptom Scores (IPSS), with the HoLEP group demonstrating a more significant decrease in IPSS (
P
< 0.001).
Conclusion
After comprehensive evaluation, HoLEP was superior to bTUR-P in terms of safety and efficacy. Therefore, HoLEP may be a preferable choice for the treatment of BPH.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V
Subject
/ Aged
/ Bladder
/ Humans
/ Lasers
/ Lasers, Solid-State - therapeutic use
/ Male
/ Medicine
/ Patients
/ Postoperative Complications - epidemiology
/ Postoperative Complications - etiology
/ Prostatic Hyperplasia - surgery
/ Transurethral Resection of Prostate - adverse effects
