Asset Details
Do you wish to reserve the book?
Promising effects of parasite-derived compounds on tumor regression: a systematic review of in vitro and in vivo studies
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Promising effects of parasite-derived compounds on tumor regression: a systematic review of in vitro and in vivo studies
Do you wish to request the book?
Promising effects of parasite-derived compounds on tumor regression: a systematic review of in vitro and in vivo studies
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Promising effects of parasite-derived compounds on tumor regression: a systematic review of in vitro and in vivo studies
2022
Overview
The parasites are repeatedly confronting their host to take advantage of nutrients for multiplication and survival. In this sense, a wide spectrum of molecules is released from both sides, with immune-regulatory activity, accompanying this biological battle. Such parasites and their valuable molecules can be directed toward microbial-based cancer therapy. Herein, we contrived a systematic review to gather information on the antitumor activity of parasite-derived compounds. Following systematic search in Web of Science, ScienceDirect, Scopus, PubMed, ProQuest and Embase until 31 December 2019, a total number of 51 articles (54 datasets) were finally included in this review. Thirteen parasitic agents were found to possess possible antitumor activity, comprising protozoan species
Toxoplasma gondii
,
Trypanosoma cruzi
,
Trichomonas vaginalis
,
Acanthamoeba castellanii
,
Besnoitia jellisoni
,
Leishmania major
,
Plasmodium yoelii
, and
Plasmodium lophurae
, as well as parasitic helminths
Toxocara canis
,
Echinococcus granulosus
,
Taenia crassiceps
,
Trichinella spiralis
, and
Schistosoma mansoni
. Most experiments were done based on antigenic preparations from
T. gondii
(16 studies),
E. granulosus
(10 studies),
T. spiralis
(8 studies), and
T. cruzi
(6 studies). Possible antitumor properties of the selected parasites were revealed in this review. However, precise molecular basis of anticancer activity for each parasite remains to be elucidated in the future.
