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Most‐read articles 2019: A year of noteworthy research
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Most‐read articles 2019: A year of noteworthy research
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Most‐read articles 2019: A year of noteworthy research
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Journal Article
Most‐read articles 2019: A year of noteworthy research
2020
Overview
In the second most‐read paper, Campbell et al reported on the first randomized controlled trial of allogeneic corneal epithelial stem cells cultured on amniotic membrane in the treatment of severe bilateral limbal stem cell deficiency, demonstrating the feasibility and safety of this approach. The most‐read papers also included important laboratory research findings, such as the third most‐read paper from Mellough et al, which compared retinal organoid differentiation from human pluripotent stem cells and revealed stage specific, cell line, and methodological differences. In another example, Zhu et al found, for the first time, that diabetes mellitus impairs the bone regenerative effect of exosomes derived from bone marrow MSCs, suggesting that the autologous transplantation of these cells to promote bone regeneration may be inadequate in these patients.
