Journal Article

Acute Kidney Injury in SARS-CoV-2 Infection: Direct Effect of Virus on Kidney Proximal Tubule Cells

Soleimani, Manoocher

2020

Overview

Coronaviruses (CoVs), including Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and the novel coronavirus disease-2 (SARS-CoV-2) are a group of enveloped RNA viruses that cause a severe respiratory infection which is associated with a high mortality [...]

• Publisher: MDPI AG,MDPI
• Subject: Acute Kidney Injury - mortality / Acute Kidney Injury - physiopathology / Acute Kidney Injury - prevention & control / Acute Kidney Injury - virology / Angiotensin II - pharmacology / Angiotensin-Converting Enzyme 2 / Betacoronavirus - pathogenicity / Cathepsins - metabolism / Cell Death - drug effects / Coronavirus Infections - mortality / Coronavirus Infections - pathology / Coronavirus Infections - physiopathology / Coronavirus Infections - virology / Coronaviruses / COVID-19 / Creatinine - blood / Critical Illness - mortality / Endosomes - drug effects / Endosomes - enzymology / Endosomes - metabolism / Humans / Hydrogen-Ion Concentration / Incidence / Kidney Tubules, Proximal - metabolism / Kidney Tubules, Proximal - physiopathology / Kidney Tubules, Proximal - virology / Lysosomes - drug effects / Lysosomes - enzymology / Lysosomes - metabolism / Middle East respiratory syndrome / Mortality / Pandemics / Peptidyl-Dipeptidase A - metabolism / Pneumonia, Viral - mortality / Pneumonia, Viral - pathology / Pneumonia, Viral - physiopathology / Pneumonia, Viral - virology / Receptors, Virus - metabolism / SARS-CoV-2 / Severe Acute Respiratory Syndrome - blood / Severe Acute Respiratory Syndrome - mortality / Severe Acute Respiratory Syndrome - physiopathology / Virus Internalization / Virus Replication / Viruses