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Comparative Effectiveness Questions in Oncology
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Comparative Effectiveness Questions in Oncology
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Comparative Effectiveness Questions in Oncology
Comparative Effectiveness Questions in Oncology
Journal Article

Comparative Effectiveness Questions in Oncology

2014
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Overview
High prices for cancer drugs preclude independent comparative effectiveness trials that would seek to establish equally effective but cheaper alternatives — thereby protecting the market share of expensive drugs. How can we make progress toward conducting such trials? The high cost of cancer drugs has been criticized by leading academics 1 and lamented in the popular press. 2 The average price of 1 year of treatment with a new cancer drug now exceeds $100,000, 1 and the benefits of many of these therapies — often improvement in median survival on the order of weeks to months — do not appear commensurate with their prices. 2 Expensive cancer drugs cost society in two ways. First, high prices are borne by payers each time these drugs are prescribed. And second, high prices preclude independent comparative effectiveness trials that would seek to establish equally effective . . .