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Microenvironmental regulation of tumour angiogenesis
by
Biziato, Daniela
, Petrova, Tatiana V
, De Palma, Michele
in
Adipocytes - physiology
/ Analysis
/ Angiogenesis
/ Animals
/ Blood Platelets - physiology
/ Blood vessels
/ Cancer
/ Cancer-Associated Fibroblasts - physiology
/ Cytokines
/ Eosinophils - physiology
/ Extracellular matrix
/ Extracellular Matrix - physiology
/ Extracellular Vesicles
/ Growth factors
/ Humans
/ Ionizing radiation
/ Lymphocytes - physiology
/ Macrophages - physiology
/ Mast Cells - physiology
/ Myeloid Cells - physiology
/ Neoplasms - blood supply
/ Neoplasms - drug therapy
/ Neoplasms - metabolism
/ Neovascularization
/ Neovascularization, Pathologic - physiopathology
/ Neutrophils - physiology
/ Pericytes - physiology
/ Stromal cells
/ Tumor Microenvironment - physiology
/ Tumors
/ Vascular endothelial growth factor
2017
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Microenvironmental regulation of tumour angiogenesis
by
Biziato, Daniela
, Petrova, Tatiana V
, De Palma, Michele
in
Adipocytes - physiology
/ Analysis
/ Angiogenesis
/ Animals
/ Blood Platelets - physiology
/ Blood vessels
/ Cancer
/ Cancer-Associated Fibroblasts - physiology
/ Cytokines
/ Eosinophils - physiology
/ Extracellular matrix
/ Extracellular Matrix - physiology
/ Extracellular Vesicles
/ Growth factors
/ Humans
/ Ionizing radiation
/ Lymphocytes - physiology
/ Macrophages - physiology
/ Mast Cells - physiology
/ Myeloid Cells - physiology
/ Neoplasms - blood supply
/ Neoplasms - drug therapy
/ Neoplasms - metabolism
/ Neovascularization
/ Neovascularization, Pathologic - physiopathology
/ Neutrophils - physiology
/ Pericytes - physiology
/ Stromal cells
/ Tumor Microenvironment - physiology
/ Tumors
/ Vascular endothelial growth factor
2017
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Do you wish to request the book?
Microenvironmental regulation of tumour angiogenesis
by
Biziato, Daniela
, Petrova, Tatiana V
, De Palma, Michele
in
Adipocytes - physiology
/ Analysis
/ Angiogenesis
/ Animals
/ Blood Platelets - physiology
/ Blood vessels
/ Cancer
/ Cancer-Associated Fibroblasts - physiology
/ Cytokines
/ Eosinophils - physiology
/ Extracellular matrix
/ Extracellular Matrix - physiology
/ Extracellular Vesicles
/ Growth factors
/ Humans
/ Ionizing radiation
/ Lymphocytes - physiology
/ Macrophages - physiology
/ Mast Cells - physiology
/ Myeloid Cells - physiology
/ Neoplasms - blood supply
/ Neoplasms - drug therapy
/ Neoplasms - metabolism
/ Neovascularization
/ Neovascularization, Pathologic - physiopathology
/ Neutrophils - physiology
/ Pericytes - physiology
/ Stromal cells
/ Tumor Microenvironment - physiology
/ Tumors
/ Vascular endothelial growth factor
2017
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Journal Article
Microenvironmental regulation of tumour angiogenesis
2017
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Overview
Tumours display considerable variation in the patterning and properties of angiogenic blood vessels, as well as in their responses to anti-angiogenic therapy. Angiogenic programming of neoplastic tissue is a multidimensional process regulated by cancer cells in concert with a variety of tumour-associated stromal cells and their bioactive products, which encompass cytokines and growth factors, the extracellular matrix and secreted microvesicles. In this Review, we discuss the extrinsic regulation of angiogenesis by the tumour microenvironment, highlighting potential vulnerabilities that could be targeted to improve the applicability and reach of anti-angiogenic cancer therapies.
Publisher
Nature Publishing Group
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