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Chimeric Antigen Receptor Therapy
by
June, Carl H
, Sadelain, Michel
in
Adoptive Transfer - adverse effects
/ Antigens, CD19
/ Genetic Engineering
/ Humans
/ Neoplasms - therapy
/ Receptors, Antigen, T-Cell - therapeutic use
/ Recombinant Fusion Proteins - adverse effects
/ Recombinant Fusion Proteins - therapeutic use
/ Remission Induction - methods
/ T-Lymphocytes - immunology
/ T-Lymphocytes - transplantation
2018
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Chimeric Antigen Receptor Therapy
by
June, Carl H
, Sadelain, Michel
in
Adoptive Transfer - adverse effects
/ Antigens, CD19
/ Genetic Engineering
/ Humans
/ Neoplasms - therapy
/ Receptors, Antigen, T-Cell - therapeutic use
/ Recombinant Fusion Proteins - adverse effects
/ Recombinant Fusion Proteins - therapeutic use
/ Remission Induction - methods
/ T-Lymphocytes - immunology
/ T-Lymphocytes - transplantation
2018
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Do you wish to request the book?
Chimeric Antigen Receptor Therapy
by
June, Carl H
, Sadelain, Michel
in
Adoptive Transfer - adverse effects
/ Antigens, CD19
/ Genetic Engineering
/ Humans
/ Neoplasms - therapy
/ Receptors, Antigen, T-Cell - therapeutic use
/ Recombinant Fusion Proteins - adverse effects
/ Recombinant Fusion Proteins - therapeutic use
/ Remission Induction - methods
/ T-Lymphocytes - immunology
/ T-Lymphocytes - transplantation
2018
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Journal Article
Chimeric Antigen Receptor Therapy
2018
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Overview
This review addresses T-cell engineering and synthetic immunity, with a focus on producing durable remissions in patients with treatment-refractory tumors. Toxic effects of chimeric antigen receptor therapies include cytokine release syndrome and neurologic dysfunction.
Publisher
Massachusetts Medical Society
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