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Home Blood-Pressure Monitoring in Patients Receiving Sunitinib
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Home Blood-Pressure Monitoring in Patients Receiving Sunitinib
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Home Blood-Pressure Monitoring in Patients Receiving Sunitinib
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Journal Article
Home Blood-Pressure Monitoring in Patients Receiving Sunitinib
2008
Overview
To the Editor:
The use of sunitinib, an inhibitor of the split-kinase-domain family of receptor tyrosine kinases (including vascular endothelial growth factor receptor types 1 and 2
1
), has been associated with a 15 to 25% incidence of hypertension in patients with advanced renal-cell carcinoma
2
,
3
; a similar incidence has been associated with other antiangiogenic drugs.
3
,
4
We report on 14 consecutive patients with metastatic renal-cell carcinoma who were being treated with sunitinib and in whom home monitoring of blood pressure by teletransmission revealed a rapid, marked increase in blood pressure, an effect that was not detected by casual . . .
Publisher
Massachusetts Medical Society
Subject
Angiogenesis Inhibitors - adverse effects
/ Antineoplastic Agents - adverse effects
/ Blood Pressure - drug effects
/ Blood Pressure Monitoring, Ambulatory
/ Carcinoma, Renal Cell - drug therapy
/ Humans
/ Hypertension - chemically induced
/ Kidney Neoplasms - drug therapy
