Asset Details
Do you wish to reserve the book?
CRISPR-based diagnostics
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
CRISPR-based diagnostics
Do you wish to request the book?
CRISPR-based diagnostics
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
CRISPR-based diagnostics
2021
Overview
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic acids are among the most sensitive and specific, yet most such assays require costly equipment and trained personnel. Recent developments in diagnostic technologies, in particular those leveraging clustered regularly interspaced short palindromic repeats (CRISPR), aim to enable accurate testing at home, at the point of care and in the field. In this Review, we provide a rundown of the rapidly expanding toolbox for CRISPR-based diagnostics, in particular the various assays, preamplification strategies and readouts, and highlight their main applications in the sensing of a wide range of molecular targets relevant to human health.
This Review summarizes the rapidly expanding toolbox of assays for CRISPR-based diagnostics and highlights their point-of-care applications.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
/ 45/23
/ 45/47
/ 45/62
/ 45/90
/ Assaying
/ Biomedical and Life Sciences
/ Biomedical Engineering/Biotechnology
/ Communicable Diseases - diagnosis
/ Communicable Diseases - microbiology
/ Communicable Diseases - virology
/ CRISPR
/ CRISPR-Cas Systems - genetics
/ Genetic Diseases, Inborn - diagnosis
/ Humans
/ Nucleic Acid Amplification Techniques - economics
/ Nucleic Acid Amplification Techniques - methods
