Journal Article

General Practitioners and Gut Microbiota: Surveying Knowledge and Awareness in Italy

Berardino, Massimo, Furnari, Andrea, Grattagliano, Ignazio, Scoglio, Riccardo, Prastaro, Marco, Dubini, Silvia, Marturano, Alessandro, Cantarini, Rosanna, Carofiglio, Francesco, Belvedere, Alessandra, Mastronuzzi, Tecla, Disclafani, Giuseppe, Di Bella, Floriana, Franchi, Daniele, Tosetti, Cesare, Barone, Roberto, Rossi, Alessandro, Bertolusso, Luciano

2025

Overview

Background/Objectives: The role of the intestinal microbiota in gastroenterological diseases has gained increasing relevance in general medicine. The study aimed to evaluate the knowledge and awareness of Italian general practitioners regarding gut microbiota, as well as the clinical applications of probiotics and prebiotics. Methods: The survey research involved 457 Italian general practitioners, who anonymously filled an online structured questionnaire. Results: Most respondents identified antibiotics, diet, gastrointestinal infections, and stress as factors that can modulate the gut microbiota, while a smaller proportion recognized the role of physical activity. A comparable number acknowledged the influence of obesity, smoking, and immunosuppressant drugs. Although most participants correctly defined probiotics, the concept of prebiotics was less widely understood. Probiotics were primarily prescribed for irritable bowel syndrome, suspected dysbiosis, or during antibiotic therapy, and only a portion of physicians reported routinely combining them with prebiotics. The selection of probiotic strains was mainly based on personal experience, while fecal microbiota analysis was seldom used in clinical practice. Conclusions: These findings provide an updated snapshot of current knowledge and practices regarding the microbiota in Italian general medicine and highlight critical gaps, particularly in the understanding of prebiotics and less recognized modulatory factors.

• Publisher: MDPI AG
• Subject: Age groups / Antibiotics / Disease / Exercise / Family physicians / Gastroenteritis / gastrointestinal disorders / general practice / Gut microbiota / Immunotherapy / Inflammatory bowel disease / Insomnia / Irritable bowel syndrome / Knowledge / Medical personnel / Metabolic syndrome / Obesity / Patients / Prebiotics / Probiotics / probiotics: antibiotics / Response rates / Smoking