Journal Article

Genomic selection - Revolutionary breeding practice in Domestic animals

Panigrahi, Manjit, Parida, Subhashree

2012

Overview

With more and more Single Nucleotide Polymorphisms (SNPs) being identified throughout the genome, some of those SNPs will be found to be located within candidate genes, allowing the researchers to use the candidate gene approach on a genomewide scale. SNPs have some drawbacks but when compared to other markers they are more efficient and SNP consortium is growing to meet the requirements of genome-wide scans. Genomic selection should be able to at least double the rate of genetic gain in the dairy industry but the incorporation of genomic information into the breeding programs must be carefully considered. One needs to have around 2000 genotypes means a large reference population (population with both phenotype and genotype recorded) to achieve meaningful increases in accuracy. The available information, selection objectives, production circumstances and benefit/cost analysis must be evaluated in order to decide whether or not the population is suitable for GS implementation, and which would be the most convenient way, if any, for its implementation. Animal breeders will need to lead the way on the integration of genomic and phenotypic data into a new era of genome-enabled animal improvement and management. Keywords: Breeding practice, Domestic Animals, DNA, Genome

• Publisher: Veterinary World
• Subject: Breeding / Breeding practice / Cattle / DNA / Domestic Animals / Genetic markers / Genome / Identification and classification / Natural selection / Single nucleotide polymorphisms