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Translational potential of human brain organoids
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Journal Article
Translational potential of human brain organoids
2018
Overview
The recent technology of 3D cultures of cellular aggregates derived from human stem cells have led to the emergence of tissue‐like structures of various organs including the brain. Brain organoids bear molecular and structural resemblance with developing human brains, and have been demonstrated to recapitulate several physiological and pathological functions of the brain. Here we provide an overview of the development of brain organoids for the clinical community, focusing on the current status of the field with an critical evaluation of its translational value.
Publisher
John Wiley & Sons, Inc,John Wiley and Sons Inc
Subject
