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Reducing Anhedonia in Major Depressive Disorder with Future Event Specificity Training (FEST): A Randomized Controlled Trial

by D’Argembeau, A , Hallford, D. J , Rusanov, D , Yeow, J. J. E , Raes, F , Austin, D. W , Fuller-Tyszkiewicz, M

in Activation / Anhedonia / Clinical outcomes / Clinical trials / Cognition / Cognitive behavioral therapy / Depressive personality disorders / Future / Hedonic response / Imagery / Mental depression / Mental imagery / Pleasure / Training / Treatment outcomes / Variables / Women

2023

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Reducing Anhedonia in Major Depressive Disorder with Future Event Specificity Training (FEST): A Randomized Controlled Trial

by D’Argembeau, A , Hallford, D. J , Rusanov, D , Yeow, J. J. E , Raes, F , Austin, D. W , Fuller-Tyszkiewicz, M

2023

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Reducing Anhedonia in Major Depressive Disorder with Future Event Specificity Training (FEST): A Randomized Controlled Trial

by D’Argembeau, A , Hallford, D. J , Rusanov, D , Yeow, J. J. E , Raes, F , Austin, D. W , Fuller-Tyszkiewicz, M

2023

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Journal Article

Reducing Anhedonia in Major Depressive Disorder with Future Event Specificity Training (FEST): A Randomized Controlled Trial

D’Argembeau, A,

Hallford, D. J,

Rusanov, D,

Yeow, J. J. E,

Raes, F,

Austin, D. W,

Fuller-Tyszkiewicz, M

2023

Overview

BackgroundImproving future thinking, such as characteristics of specificity, detail, and use of mental imagery, may be one means to reduce anhedonia, particularly in a Major Depressive Episode (MDE) in which future thinking is impaired. The current study aimed to test this using a validated program, Future Event Specificity Training (FEST).MethodsParticipants (N = 177; 80.8% women; M age = 43.7, SD = 11.8) with a current depressive episode with anhedonia and high symptom severity were randomized to FEST or no FEST. Future thinking, anhedonia-related variables, and other clinical outcomes were assessed at baseline, one- and three-month follow-up.ResultsRelative to the control group, FEST was associated with significantly improved future thinking characteristics, a reduced likelihood of anhedonia (35.1% vs. 61.1%, p = .015), improvements on other anhedonia-related variables such as anticipatory (d = 0.63, p = .004) and anticipated pleasure for future events (d = 0.77, p < .001), and desirable clinical outcomes such as less people meeting criteria for an MDE (37.8% vs. 64.8%, p = .011), higher behavioural activation (d = 0.71, p = .001) and improved global functioning (d = 0.52, p = .017). Changes in future thinking were found to mediate the effect of FEST on anhedonia.ConclusionThe quality of future thinking can be enhanced in Major Depression, and this leads to a substantially reduced likelihood of anhedonia, other significant clinical effects, and functional gains.

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Publisher

Springer Nature B.V

Subject

/ Cognitive behavioral therapy

/ Depressive personality disorders