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An integrated behavioural intervention combined with varenicline for heavy-drinking smokers: a randomized pilot study
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An integrated behavioural intervention combined with varenicline for heavy-drinking smokers: a randomized pilot study
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An integrated behavioural intervention combined with varenicline for heavy-drinking smokers: a randomized pilot study
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Journal Article
An integrated behavioural intervention combined with varenicline for heavy-drinking smokers: a randomized pilot study
2020
Overview
Combined smoking and heavy drinking is a significant health burden. Varenicline, an efficacious tobacco pharmacotherapy that also shows promise for drinking, has yielded mixed results among heavy-drinking smokers. This pilot study investigated integrated tobacco and alcohol counselling plus varenicline for this vulnerable group.
Twelve-week parallel, randomized controlled pilot trial of two behavioural interventions in combination with open-label varenicline. Participants were randomized using computer-generated tables, stratified by sex.
Outpatient academic medical centre research clinic.
Volunteers who reported smoking and heavy drinking and sought tobacco or alcohol treatment (
= 26). Intervention. (1) Integrated tobacco + alcohol counselling (INT;
= 13) or (2) counselling focused on their presenting concern (i.e., tobacco or alcohol) (SINGLE;
= 13), plus varenicline (2 mg) for 12 weeks.
Feasibility/acceptability, smoking quit rates and heavy drinking.
INT feasibility/acceptability was high among men but not women. More participants quit smoking in INT than SINGLE. This outcome was only in men, not significant, but had a medium effect size. Both conditions yielded significant drinking reductions.
Integrated tobacco and alcohol behavioural counselling plus varenicline may be feasible and promote smoking cessation among men who smoke and drink heavily, but a larger sample is needed to replicate this finding.
