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Hypereosinophilic syndrome—a rare adverse event of anti-cytokine treatment in rheumatoid arthritis resolved after Janus kinase inhibitor therapy
by
Kašperová Stela
, Šteňová Emőke
, Babál Pavel
, Tarabčáková Lenka
in
Allergies
/ Atopy
/ Blood cancer
/ Blood diseases
/ Cytokines
/ Dyspnea
/ Eczema
/ Enzyme inhibitors
/ Eosinophilia
/ Janus kinase
/ Leukocytes (eosinophilic)
/ Malignancy
/ Respiration
/ Rheumatoid arthritis
/ Vasculitis
2020
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Hypereosinophilic syndrome—a rare adverse event of anti-cytokine treatment in rheumatoid arthritis resolved after Janus kinase inhibitor therapy
by
Kašperová Stela
, Šteňová Emőke
, Babál Pavel
, Tarabčáková Lenka
in
Allergies
/ Atopy
/ Blood cancer
/ Blood diseases
/ Cytokines
/ Dyspnea
/ Eczema
/ Enzyme inhibitors
/ Eosinophilia
/ Janus kinase
/ Leukocytes (eosinophilic)
/ Malignancy
/ Respiration
/ Rheumatoid arthritis
/ Vasculitis
2020
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While trying to remove the title from your shelf something went wrong :( Kindly try again later!
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Hypereosinophilic syndrome—a rare adverse event of anti-cytokine treatment in rheumatoid arthritis resolved after Janus kinase inhibitor therapy
by
Kašperová Stela
, Šteňová Emőke
, Babál Pavel
, Tarabčáková Lenka
in
Allergies
/ Atopy
/ Blood cancer
/ Blood diseases
/ Cytokines
/ Dyspnea
/ Eczema
/ Enzyme inhibitors
/ Eosinophilia
/ Janus kinase
/ Leukocytes (eosinophilic)
/ Malignancy
/ Respiration
/ Rheumatoid arthritis
/ Vasculitis
2020
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Hypereosinophilic syndrome—a rare adverse event of anti-cytokine treatment in rheumatoid arthritis resolved after Janus kinase inhibitor therapy
Journal Article
Hypereosinophilic syndrome—a rare adverse event of anti-cytokine treatment in rheumatoid arthritis resolved after Janus kinase inhibitor therapy
2020
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Overview
Eosinophilia is uncommon in early rheumatoid arthritis (RA). The most frequent causes of hypereosinophilia during RA treatment are atopic eczema, allergy, helminth infection, haematological malignancy and drug-associated complications. The pathogenesis of this abnormality associated with anti-cytokine therapy is still unknown. We report the case of a young woman with RA and eosinophilia accompanied by systemic symptoms such as dyspnoea, fluid retention and eosinophilic vasculitis. An interesting observation was the persistence of eosinophilia during treatment with various biologics and its normalization after switching to the Janus kinase inhibitor baricitinib.
Publisher
Springer Nature B.V
Subject
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