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Radioimmunotherapy of B-Cell Lymphoma with 131IAnti-B1 (Anti-CD20) Antibody
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Radioimmunotherapy of B-Cell Lymphoma with 131IAnti-B1 (Anti-CD20) Antibody
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Journal Article
Radioimmunotherapy of B-Cell Lymphoma with 131IAnti-B1 (Anti-CD20) Antibody
1993
Overview
Despite the use of various combined chemotherapeutic regimens for advanced-stage intermediate- and high-grade lymphomas, roughly half of patients treated do not have a complete remission or eventually have a relapse after a remission. This situation has not improved noticeably in almost two decades
1
,
2
. Treatment with standard-dose salvage chemotherapy rarely results in durable remissions and often has serious toxicity. Although the use of high-dose chemotherapy with bone marrow transplantation has shown promise, not all patients derive long-term benefit from this treatment
3
. Furthermore, a curative treatment for patients with advanced low-grade lymphoma still remains to be clearly established
4
. . . .
Publisher
Massachusetts Medical Society
Subject
/ Aged
/ Antibodies, Monoclonal - therapeutic use
/ Antigens
/ Antigens, Differentiation, B-Lymphocyte - immunology
/ Biological and medical sciences
/ Hematologic and hematopoietic diseases
/ Humans
/ Iodine Radioisotopes - therapeutic use
/ Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
/ Lymphoma
/ Lymphoma, B-Cell - diagnostic imaging
/ Lymphoma, B-Cell - radiotherapy
/ Male
/ Patients
