Asset Details
Do you wish to reserve the book?
Rapid diagnostic tests for Lassa fever: what do we aim for?
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Rapid diagnostic tests for Lassa fever: what do we aim for?
Do you wish to request the book?
Rapid diagnostic tests for Lassa fever: what do we aim for?
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Rapid diagnostic tests for Lassa fever: what do we aim for?
2024
Overview
Lassa virus (LASV) is a high-consequence pathogen endemic to west Africa that causes annual outbreaks with substantial mortality. Besides transmission from the rodent reservoir to humans, human-to-human transmission can occur through contact with blood and other bodily fluids.1,2 To date, people in endemic regions presenting with the initially unspecific clinical symptoms of Lassa fever are mostly tested for LASV only after empirical treatment with antimalarials and antibiotics has failed. The sensitivity of the test was poorly correlated with viral load, as false-negative test results also occurred in highly viraemic individuals.3 Based on the understanding that RDTs are often imperfect diagnostic tools, they could still have a highly positive impact on patient management when used wisely. [...]to correctly interpret the results of this study, we need to first ask what the minimum acceptable test performance characteristics of an RDT are for this high-consequence pathogen. [...]tests have proven sufficiently accurate in the field, we must continue to rely on an accelerated implementation of molecular diagnostic assays for Lassa fever diagnosis.
Publisher
Elsevier Ltd,Elsevier Limited
