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St John’s wort (Hypericum perforatum)-induced psychosis: a case report
by
Ferrara, Maria
, Mungai, Francesco
, Starace, Fabrizio
in
Adult
/ Anticoagulants
/ Antidepressants
/ Antidepressive Agents - adverse effects
/ Antidepressive Agents - pharmacology
/ Birth control
/ Case Report
/ Case reports
/ Clinical trials
/ Complementary and alternative medicines
/ Depressive Disorder, Major - drug therapy
/ Depressive Disorder, Major - psychology
/ Drug dosages
/ Enzymes
/ Family Medicine
/ General Practice
/ Helicobacter Infections - drug therapy
/ Herbal medicine
/ Herbal remedies
/ Humans
/ Hypericum
/ Hypericum - adverse effects
/ Internal Medicine
/ Male
/ Medicine
/ Medicine & Public Health
/ Mental depression
/ Mental health
/ Pharmaceuticals
/ Phytotherapy - adverse effects
/ Primary Care Medicine
/ Psychiatry
/ Psychoses, Substance-Induced - diagnosis
/ Psychosis
/ Psychotropic drugs
/ Public Health
/ Self Medication - adverse effects
/ Self Medication - psychology
/ St John’s wort
/ Substance abuse treatment
/ Substance-Related Disorders - drug therapy
/ Substance-Related Disorders - psychology
/ Surgical Oncology
2017
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St John’s wort (Hypericum perforatum)-induced psychosis: a case report
by
Ferrara, Maria
, Mungai, Francesco
, Starace, Fabrizio
in
Adult
/ Anticoagulants
/ Antidepressants
/ Antidepressive Agents - adverse effects
/ Antidepressive Agents - pharmacology
/ Birth control
/ Case Report
/ Case reports
/ Clinical trials
/ Complementary and alternative medicines
/ Depressive Disorder, Major - drug therapy
/ Depressive Disorder, Major - psychology
/ Drug dosages
/ Enzymes
/ Family Medicine
/ General Practice
/ Helicobacter Infections - drug therapy
/ Herbal medicine
/ Herbal remedies
/ Humans
/ Hypericum
/ Hypericum - adverse effects
/ Internal Medicine
/ Male
/ Medicine
/ Medicine & Public Health
/ Mental depression
/ Mental health
/ Pharmaceuticals
/ Phytotherapy - adverse effects
/ Primary Care Medicine
/ Psychiatry
/ Psychoses, Substance-Induced - diagnosis
/ Psychosis
/ Psychotropic drugs
/ Public Health
/ Self Medication - adverse effects
/ Self Medication - psychology
/ St John’s wort
/ Substance abuse treatment
/ Substance-Related Disorders - drug therapy
/ Substance-Related Disorders - psychology
/ Surgical Oncology
2017
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St John’s wort (Hypericum perforatum)-induced psychosis: a case report
by
Ferrara, Maria
, Mungai, Francesco
, Starace, Fabrizio
in
Adult
/ Anticoagulants
/ Antidepressants
/ Antidepressive Agents - adverse effects
/ Antidepressive Agents - pharmacology
/ Birth control
/ Case Report
/ Case reports
/ Clinical trials
/ Complementary and alternative medicines
/ Depressive Disorder, Major - drug therapy
/ Depressive Disorder, Major - psychology
/ Drug dosages
/ Enzymes
/ Family Medicine
/ General Practice
/ Helicobacter Infections - drug therapy
/ Herbal medicine
/ Herbal remedies
/ Humans
/ Hypericum
/ Hypericum - adverse effects
/ Internal Medicine
/ Male
/ Medicine
/ Medicine & Public Health
/ Mental depression
/ Mental health
/ Pharmaceuticals
/ Phytotherapy - adverse effects
/ Primary Care Medicine
/ Psychiatry
/ Psychoses, Substance-Induced - diagnosis
/ Psychosis
/ Psychotropic drugs
/ Public Health
/ Self Medication - adverse effects
/ Self Medication - psychology
/ St John’s wort
/ Substance abuse treatment
/ Substance-Related Disorders - drug therapy
/ Substance-Related Disorders - psychology
/ Surgical Oncology
2017
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St John’s wort (Hypericum perforatum)-induced psychosis: a case report
Journal Article
St John’s wort (Hypericum perforatum)-induced psychosis: a case report
2017
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Overview
Background
St John’s wort (
Hypericum perforatum
) has been known for centuries for its therapeutic properties and its efficacy as an antidepressant has been confirmed by a growing body of evidence. During the last two decades it has also come to prominence with a wider public, due to advertising efforts across Europe and United States of America. However, its availability without prescription, as an over-the-counter medication, raises some concern regarding its clinical management and unsupervised administration to individuals with psychopathological risks. To date, the evidence available regarding the administration of
Hypericum
in people with severe mental health problems is still meager and refers mainly to affective disorder spectrum or psychotic relapse in people with established diagnoses. To the best of our knowledge, this is the first report regarding the onset of psychotic features in a patient presenting with psychotic diathesis.
Case presentation
The case discussed in this report is a 25-year-old white man, not known to the psychiatric services, with a history of brief and self-remitting drug-induced psychosis and a positive family history of psychotic depression. He was admitted to hospital due to the onset of florid psychotic symptoms concomitant with self-administration of
Hypericum perforatum
.
Conclusions
The aim of this report is to promote further systematic research, draw the attention of clinicians to the potential risks of
Hypericum
precipitating psychosis, and raise awareness among health professionals to investigate and caution their patients on the haphazard use of phytotherapeutics such as
Hypericum
.
Publisher
BioMed Central,Springer Nature B.V,BMC
Subject
/ Antidepressive Agents - adverse effects
/ Antidepressive Agents - pharmacology
/ Complementary and alternative medicines
/ Depressive Disorder, Major - drug therapy
/ Depressive Disorder, Major - psychology
/ Enzymes
/ Helicobacter Infections - drug therapy
/ Humans
/ Male
/ Medicine
/ Phytotherapy - adverse effects
/ Psychoses, Substance-Induced - diagnosis
/ Self Medication - adverse effects
/ Self Medication - psychology
/ Substance-Related Disorders - drug therapy
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