Journal Article

Contemporary, non-invasive imaging diagnosis of chronic coronary artery disease

van Rosendael, Alexander, Bax, Jeroen J, Blankstein, Ron, Sengupta, Partho P, Knuuti, Juhani, Marwick, Thomas, van der Bijl, Pieter, Nieman, Koen, Kwong, Raymond, Gulati, Martha, Bangalore, Sripal, Saraste, Antti

2025

Overview

Coronary artery disease is one of the leading causes of morbidity and mortality worldwide. Although it can present with an acute coronary syndrome, it is often characterised by long periods of stability, known as chronic coronary artery disease. This Review presents a comprehensive overview of the diagnosis of the disease, with a focus on cardiac imaging. We discuss various cardiac imaging modalities, including CT coronary angiography, stress echocardiogram, stress single-photon emission CT, PET, and stress cardiac magnetic resonance. We also compare the roles of anatomical (eg, CT coronary angiography) versus functional (eg, stress echocardiogram) tests and examine the potential utility of artificial intelligence in more detail.

• Publisher: Elsevier Ltd,Elsevier Limited
• Subject: Acute coronary syndromes / Angina pectoris / Angiography / Artificial Intelligence / Cardiac Imaging Techniques - methods / Cardiology / Cardiovascular disease / Chronic Disease / Computed tomography / Computed Tomography Angiography / Coronary Angiography - methods / Coronary artery disease / Coronary Artery Disease - diagnosis / Coronary Artery Disease - diagnostic imaging / Coronary vessels / Diabetes / Diagnosis / Diagnostic tests / Echocardiography / Echocardiography, Stress - methods / Electrocardiography / Family medical history / Heart diseases / Humans / Hypertension / Internal Medicine / Ischemia / Magnetic resonance / Magnetic Resonance Imaging / Medical imaging / Metabolic disorders / Morbidity / Mortality / Pharmacists / Photon emission / Positron-Emission Tomography / Risk factors / Tomography, Emission-Computed, Single-Photon / Vein & artery diseases