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Does the etiology of cardiac amyloidosis determine the myocardial uptake of 18F-NaF PET/CT?

by Diodato, Stefania , Gagliardi, Christian , Nanni, Cristina , Rapezzi, Claudio , Milandri, Agnese , Fanti, Stefano , Tabacchi, Elena , Guidalotti, Pierluigi , Lodi, Filippo , Bonfiglioli, Rachele , Lorenzini, Massimiliano

in [18F]-NaF PET/CT / Amyloidosis / Amyloidosis - diagnostic imaging / Amyloidosis - etiology / Amyloidosis - metabolism / Biopsy / cardiac amyloidosis / Cardiology / Cardiomyopathies - diagnostic imaging / Cardiomyopathies - etiology / Cardiomyopathies - metabolism / Cardiomyopathy / Diagnosis, Differential / Etiology / Humans / Images that Teach / Imaging / Medical imaging / Medicine / Medicine & Public Health / Metabolic Clearance Rate / Middle Aged / Nuclear Medicine / Patients / PET/CT imaging / Positron Emission Tomography Computed Tomography - methods / Radiology / Radiopharmaceuticals - pharmacokinetics / Tissue Distribution / Ultrasonic imaging

2017

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Does the etiology of cardiac amyloidosis determine the myocardial uptake of 18F-NaF PET/CT?

2017

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Does the etiology of cardiac amyloidosis determine the myocardial uptake of 18F-NaF PET/CT?

2017

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Journal Article

Does the etiology of cardiac amyloidosis determine the myocardial uptake of 18F-NaF PET/CT?

Diodato, Stefania,

Gagliardi, Christian,

Nanni, Cristina,

Rapezzi, Claudio,

Milandri, Agnese,

Fanti, Stefano,

Tabacchi, Elena,

Guidalotti, Pierluigi,

Lodi, Filippo,

Bonfiglioli, Rachele,

Lorenzini, Massimiliano

2017

Overview

Cardiac amyloidosis (CA) leads to variable degrees of myocardial infiltration with a final echocardiographic phenotype of “hypertrophy.” Although many non-invasive imaging techniques (MRI, CT, scintigraphy, PET) are useful, the definitive diagnosis is still based on myocardial histology. We explored the possible role of [18F]-NaF PET/CT in the diagnosis of this disease in two cases with wild-type (ATTRwt) or mutant (ATTRm) Ile68Leu transthyretin (TTR)-related CA.

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Publisher

Elsevier Inc,Springer US,Springer Nature B.V

Subject

[18F]-NaF PET/CT

/ Amyloidosis

/ Amyloidosis - diagnostic imaging

/ Amyloidosis - etiology

/ Amyloidosis - metabolism

/ Biopsy

/ cardiac amyloidosis