Asset Details
Do you wish to reserve the book?
Effective Antioxidants as Plausible Ligands in Chromium(III) Supplementation: How Complexation Modulates Catechol-Based Polyphenols
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effective Antioxidants as Plausible Ligands in Chromium(III) Supplementation: How Complexation Modulates Catechol-Based Polyphenols
Do you wish to request the book?
Effective Antioxidants as Plausible Ligands in Chromium(III) Supplementation: How Complexation Modulates Catechol-Based Polyphenols
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effective Antioxidants as Plausible Ligands in Chromium(III) Supplementation: How Complexation Modulates Catechol-Based Polyphenols
2025
Overview
This study examines the impact of metal coordination on the antioxidant and pro-oxidant properties of 3,4-dihydroxybenzoic acid (3,4-DHBA) and caffeic acid (CA). Their Na(I), K(I) salts and Cr(III) complexes were evaluated in vitro using radical scavenging assays (ABTS, DPPH, hydroxyl, and superoxide), ferric- and cupric-reducing power, and inhibition of linoleic acid peroxidation. Alkali metal coordination generally decreased radical scavenging activity, though K complexes and Cr–3,4-DHBA improved lipid peroxidation inhibition. Cr(III) chelation produced ligand-dependent effects: it markedly increased the reducing power of CA while reducing that of 3,4-DHBA and uniquely promoted pro-oxidant behavior in CA under superoxide conditions. These outcomes reflect how chromium chelation alters electronic distribution and charge transfer, enhancing reducing power in single-electron transfer assays while enabling redox cycling in radical scavenging systems, underscoring its dual and ligand-dependent biological significance.
Publisher
MDPI AG
